منابع مشابه
Loss of Uch-L1 and Uch-L3 leads to neurodegeneration, posterior paralysis and dysphagia.
Altered function of the ubiquitin pathway has been implicated in the etiology of neurodegeneration. For example, gracile axonal dystrophy (gad) mutant mice, which harbor a deletion within the gene encoding ubiquitin C-terminal hydrolase L1 (Uch-L1), display sensory ataxia followed by posterior paralysis and lethality. We previously showed that mice homozygous for a targeted deletion of the rela...
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ژورنال
عنوان ژورنال: Zeitschrift für celtische Philologie
سال: 1912
ISSN: 0084-5302,1865-889X
DOI: 10.1515/zcph.1912.8.1.347